What are Pseudoindoxyl Alkaloids and 7-OH in Kratom?

Structure of Mitragynine Pseudoindoxyl

Kratom (Mitragyna speciosa) is rich in active compounds, but two of the most potent are 7-hydroxymitragynine (7-OH) and Kratom Pseudoindoxyl. These alkaloids are gaining attention for their powerful effects and potential therapeutic value, especially in pain relief, mood enhancement, and future medical research.

1. What Is 7-OH Kratom?

7-hydroxymitragynine (7-OH) is a natural oxidized derivative of mitragynine, the primary alkaloid in kratom leaves. While found in small amounts in raw kratom powder, it is often concentrated in kratom extracts like our 7-OH Kratom Extract.

7-hydroxymitragynine compound

Key Benefits of 7-OH:

• Strong analgesic (pain-relieving) effects

• Fast-acting (onset within 15–20 minutes)

• Works at lower doses than standard kratom powder

• Often preferred by experienced users or those with high tolerance

2. What Are Kratom Pseudoindoxyl Alkaloids?

Kratom Pseudoindoxyl Alkaloids are metabolites of mitragynine and 7-OH that forms inside the body after consumption. Recent studies show it has unique opioid-like properties that differ from both morphine and 7-OH. It may hold potential as a safer alternative to traditional pain medications with reduced tolerance or dependency risks.

Why It’s Important:

• Shows promise in preclinical pain research

• Thought to be more receptor-selective than morphine

• May cause less respiratory depression than conventional opioids

• Being explored for pharmaceutical development

3. How Is 7-OH Kratom Made?

While 7-OH naturally occurs in kratom leaves, it can also be enhanced through specialized extraction and oxidation processes performed in regulated laboratories. This is how we produce concentrated extracts like our premium 7-OH Kratom Tincture.

⚠️ Note: Making 7-OH at home is not recommended or legal in some regions. Always purchase from lab-tested, trusted sources.

4. Can You Make Kratom Pseudoindoxyl?

Kratom Pseudoindoxyl is not commercially extracted—it is formed inside the body as your liver metabolizes kratom alkaloids like mitragynine and 7-OH.

Because of its complex transformation, there is no legal or safe DIY method to produce this compound externally. It is primarily studied in research labs for potential pharmaceutical applications.

5. 7-OH vs. Pseudoindoxyl: A Quick Comparison

Feature	7-OH Kratom	Kratom Pseudoindoxyl
Origin	Found in kratom & extracts	Forms in body post-ingestion
Strength	Very strong	Potentially stronger (research)
Legal Status	Available in extracts	Not sold as a product
Use	Pain, mood, energy	Research/medical interest only
Available At	Roots Kava Bar NY	N/A

If you're exploring the strongest kratom options, 7-OH Kratom Extract is a legal, fast-acting solution used by many for relief, focus, and mood support. While Kratom Pseudoindoxyl isn’t something you can buy or make, understanding its role highlights the complex power of kratom alkaloids.

Try It Yourself

Our 7-OH Kratom Extract is available in-store and online with discreet shipping. Shop now and experience the difference that full-spectrum kratom science can offer.

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