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What are Pseudoindoxyl Alkaloids and 7-OH in Kratom?


Pseudoindoxyl Alkaloids Structure
Structure of Mitragynine Pseudoindoxyl

Kratom (Mitragyna speciosa) is rich in active compounds, but two of the most potent are 7-hydroxymitragynine (7-OH) and Kratom Pseudoindoxyl. These alkaloids are gaining attention for their powerful effects and potential therapeutic value, especially in pain relief, mood enhancement, and future medical research.


  1. What Is 7-OH Kratom?

7-hydroxymitragynine (7-OH) is a natural oxidized derivative of mitragynine, the primary alkaloid in kratom leaves. While found in small amounts in raw kratom powder, it is often concentrated in kratom extracts like our 7-OH Kratom Extract.

7-hydroxymitragynine to Pseodoindoxyl Alkaloids
7-hydroxymitragynine compound

Key Benefits of 7-OH:

  • Strong analgesic (pain-relieving) effects

  • Fast-acting (onset within 15–20 minutes)

  • Works at lower doses than standard kratom powder

  • Often preferred by experienced users or those with high tolerance


  1. What Are Kratom Pseudoindoxyl Alkaloids?

Kratom Pseudoindoxyl Alkaloids are metabolites of mitragynine and 7-OH that forms inside the body after consumption. Recent studies show it has unique opioid-like properties that differ from both morphine and 7-OH. It may hold potential as a safer alternative to traditional pain medications with reduced tolerance or dependency risks.


Why It’s Important:


  1. How Is 7-OH Kratom Made?

While 7-OH naturally occurs in kratom leaves, it can also be enhanced through specialized extraction and oxidation processes performed in regulated laboratories. This is how we produce concentrated extracts like our premium 7-OH Kratom Tincture.

⚠️ Note: Making 7-OH at home is not recommended or legal in some regions. Always purchase from lab-tested, trusted sources.

4. Can You Make Kratom Pseudoindoxyl?

Kratom Pseudoindoxyl is not commercially extracted—it is formed inside the body as your liver metabolizes kratom alkaloids like mitragynine and 7-OH.

Because of its complex transformation, there is no legal or safe DIY method to produce this compound externally. It is primarily studied in research labs for potential pharmaceutical applications.


  1. 7-OH vs. Pseudoindoxyl: A Quick Comparison

Feature

7-OH Kratom

Kratom Pseudoindoxyl

Origin

Found in kratom & extracts

Forms in body post-ingestion

Strength

Very strong

Potentially stronger (research)

Legal Status

Available in extracts

Not sold as a product

Use

Pain, mood, energy

Research/medical interest only

Available At

N/A

If you're exploring the strongest kratom options, 7-OH Kratom Extract is a legal, fast-acting solution used by many for relief, focus, and mood support. While Kratom Pseudoindoxyl isn’t something you can buy or make, understanding its role highlights the complex power of kratom alkaloids.


Try It Yourself

Our 7-OH Kratom Extract is available in-store and online with discreet shipping. Shop now and experience the difference that full-spectrum kratom science can offer.




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We do not ship to the following US states, counties, and cities where any of our botanicals are banned: Often considered: Alabama, Arkansas, Indiana, Rhode Island, Vermont, Wisconsin, Sarasota County (FL), Union County (NC), and San Diego (CA).

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The products offered at Roots Kava Bar have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease.

Please consult your healthcare provider before consuming kava or other herbal supplements, especially if you are pregnant, nursing, have a medical condition, or are taking any medication.

Consumption of kava may cause drowsiness. Do not drive or operate heavy machinery after consuming kava. Please enjoy responsibly.

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